Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is a rare condition characterized DARK COCONUT SUGAR by emotional and behavioral disturbances, dyskinesias, and extrapyramidal signs.It occurs in young women of reproductive age and is classically described as a paraneoplastic phenomenon.We present a 36-year-old, HIV-positive female who was admitted to the hospital in an acute confusional state, with a stiff posture, periods of motor agitation, and myoclonic jerks of the hands.Her mental state progressively deteriorated.
Without evidence of infection, the presence of anti-NMDAR antibodies both in serum and cerebrospinal fluid Hydro 6 Parts clinched the diagnosis of autoimmune encephalitis.No evidence of neoplastic disease was found, and the beneficial response to immunosuppressive therapy was exceptional.This is the first report of anti-NMDAR encephalitis in an HIV-infected individual, reminding us that autoimmune encephalitis should be included in the differential diagnosis of a young patient presenting in an acute confusional state.